Chemistry (CHE)

CHE 4207  Preparative Inorganic Chemistry  (2)  
Pre-requisite(s): CHE 3238 and 4302  

A wide range of experimental techniques currently used in preparative inorganic chemistry research. Such techniques include dry bag, inert atmosphere, ion-exchange, and vacuum line manipulations; electrolytic, non-aqueous solvent, and tube furnace preparations. Emphasis will be given to both the preparation and characterization of compounds prepared in the laboratory.

CHE 4217  Instrumental Analysis Laboratory  (2)  
Pre-requisite(s): CHE 4225 or 4227, and either credit or concurrent registration in CHE 4316  

Laboratory work in instrumental analysis with an emphasis on spectroscopy, separations, and electrochemical methods.

CHE 4227  Physical Chemistry Laboratory I  (2)  
Pre-requisite(s): CHE 2416 and credit or concurrent enrollment in CHE 4321  

Techniques of physical property measurement, data analysis, and interpretation, with emphasis on thermodynamics, electrochemistry, surface chemistry, solutions, and kinetics. Instruction in effective report writing.

CHE 4228  Physical Chemistry Laboratory II  (2)  
Pre-requisite(s): CHE 4225 or 4227, and credit or concurrent enrollment in CHE 4322  

Advanced work in measurement and data analysis techniques, with emphasis on lasers, molecular spectroscopy, and photochemistry. Instruction in effective report writing.

CHE 4237  Advanced Organic Laboratory  (2)  
Pre-requisite(s): CHE 3238 and 3332  

Advanced organic synthesis, purification and analysis techniques, including the use of instrumental methods, such as inert atmosphere techniques and modern analytical and preparative chromatography.

CHE 4307  Modern Inorganic Chemistry II  (3)  
Pre-requisite(s): CHE 4302  

Advanced topics in inorganic chemistry; molecular symmetry with applications to electronic structure and spectroscopy; reaction kinetics and mechanisms; inorganic synthesis and catalysis; bioinorganic chemistry.

CHE 4316  Instrumental Analysis  (3)  
Pre-requisite(s): CHE 4321 or 4327  

Introduction to instrumental methods of analysis including spectroscopy, separations, and electrochemical methods.

CHE 4321  Physical Chemistry I  (3)  
Pre-requisite(s): CHE 2416, MTH 2321, and PHY 1430; and CHE 3332 or consent of instructor  

Gases, liquids and solids, phase changes, electrochemistry, and the principles of kinetics and thermodynamics. (Not applicable to a major in biochemistry.)

CHE 4322  Physical Chemistry II  (3)  
Pre-requisite(s): CHE 2416, MTH 2321, and PHY 1430; and CHE 3332 or consent of instructor  

Postulates of quantum mechanics. Application of quantum theory to simple models: particle in a box, rigid rotor, and harmonic oscillator. Electronic, rotational, and vibrational motion in molecules. Molecular energy levels and spectra. Electronic structure of atoms and molecules. Basic concepts of statistical thermodynamics.

CHE 4334  Organic Spectroscopy  (3)  
Pre-requisite(s): Either CHE 3238 and 3332 with grades of B or above; or CHE 3332 with a grade of B or above and credit or concurrent enrollment in CHE 4237  

The most common spectroscopic methods including infrared, ultraviolet-visible, nuclear magnetic resonance and mass spectroscopies, with emphasis on the practical use of NMR and MS in structure determination problems.

CHE 4341  General Biochemistry  (3)  
Pre-requisite(s): CHE 3332 with a grade of C or better  

Structure and dynamics of compounds of biological interest. (Students may not receive credit for both BIO 4307 and CHE 4341.)

CHE 4342  Topics in Human Biochemistry  (3)  
Pre-requisite(s): A grade of C or better in CHE 3332; and either a grade of C or better in CHE 4341 or a grade of B or better in BIO 4307 Topics in selected areas of human biochemistry such as hormone action, neurotransmission, vision, digestion, transport  
CHE 5050  Chemistry Colloquium  (0)  

A weekly, graduate-level seminar featuring speakers from science departments at Baylor, industry, medical schools, and other universities.

CHE 5101  Responsible Conduct of Research  (1)  

Covers ethical and regulatory issues regarding modern scientific research.

CHE 5150  Graduate Seminar  (1)  
Pre-requisite(s): Enrollment in the graduate program  

A seminar program in which students will be required to present a paper for evaluation before the graduate faculty and other graduate students. Must be taken two times for the master's degree and three times for the Ph.D. degree.

CHE 5179  Research Seminar  (1)  
Pre-requisite(s): Enrollment in the graduate program  

A weekly colloquium in which students are required to present papers and study the literature in the area of their research project. May be repeated, but no more than three semester hours may be counted on a master's degree and no more than six may be counted on the Ph.D. degree. May not be used to fulfill course work requirements.

CHE 5260  Scientific Communication  (2)  
Pre-requisite(s): Graduate standing  

This experiential-learning course, designed for first-year graduate students, provides instruction and practice in the development of an original research proposal. Strategies for effective oral and written communication of scientific information are emphasized, along with the importance of mastering primary literature in the chosen field of interest.

CHE 5301  Chemistry of the Elements  (3)  
Pre-requisite(s): CHE 4301 or consent of instructor  

Comparative chemistry of the Main Group and Transition elements; relationships between structure and reactivity; energetics and kinetics of inorganic reactions.

CHE 5302  Symmetry and Group Theory in Chemistry  (3)  
Pre-requisite(s): CHE 4301 or consent of instructor  

Application of symmetry and group theory to chemical bonding and spectroscopic selection rules; use of character tables; electronic and vibration spectroscopy.

CHE 5303  Physical Methods in Inorganic Chemistry  (3)  
CHE 5304  Special Topics in Inorganic Chemistry  (3)  

This course concerns characterization of redox active inorganic complexes by a number of physical methods. Topics covered include electronic structure and geometry (Group theory, MO diagrams), orbital energies of ground and excited states (UV-vis absorbance/emission), and ways of accessing and interpreting changes in oxidation states (electrochemistry, Marcus theory). Symmetry and group theory are fundamental to many of these applications, and will be introduced.

CHE 5305  Organometallic Chemistry and Homogenous Catalysis  (3)  
Pre-requisite(s): Consent of instructor  

Chemical reactions of organometallic compounds and their role in homogeneous catalysis with emphasis on the transition metals. Reactivity patterns and reaction mechanisms in organometallic chemistry. Factors influencing stabilities and reactivities of metal-carbon bonds.

CHE 5306  Bioinorganic Chemistry  (3)  

An overview of the biological chemistry of metal ions. Emphasis will be on the structural motifs of metalloproteins and their associated reactivities in relation to physiological function.

CHE 5310  Advanced Chemical Instrumentation  (3)  
Pre-requisite(s): CHE 4217 and 4316  

Principles of chemical instrumentation, including principles of electronic signal handling, sources of noise and signal-to-noise theory, noise reduction techniques such as modulation and phase-sensitive detection, introductory information theory, introductory geometrical optics, and vacuum systems.

CHE 5312  Advanced X-omics Mass Spectrometry  (3)  

Understanding of chemical interactions within complex mixtures, such as biological fluids and environmental samples, requires simultaneous characterization of all sample components at the molecular level. State-of-the art high performance mass spectrometers, coupled to various separation techniques, provide the necessary sensitivity, resolving power, and multidimensionality for comprehensive characterization of complex mixtures. This course covers current topics in x-omics research (including genomics, metabolomics, petroleomics, and proteomics) with a focus on bioanalytical aspects of utilizing ion generation methods, ion-molecule reactions, ion fragmentation techniques, particle analyzers/detectors, and multidimensional data generation/analyses. Moreover, fundamental aspects and practical significance of accurate mass measurements and conformational analyses in biomedical research and drug development strategies are presented.

CHE 5314  Separation Science  (3)  
Pre-requisite(s): CHE 4316 or consent of instructor  

Theoretical foundations and practical applications of analytical separations with emphasis on gas, liquid, supercritical fluid, and ion chromatographies.

CHE 5315  Electroanalytical Chemistry  (3)  
Pre-requisite(s): CHE 4316 or consent of instructor  

Modern electroanalytical techniques and their application to analytical, kinetic, mechanistic, and synthetic problems.

CHE 5316  Analytical Spectroscopy  (3)  
Pre-requisite(s): CHE 4316  

Theoretical and practical aspects of analytical optical spectroscopy with emphasis on instrumentation.

CHE 5320  Thermodynamics and Statistical Thermodynamics  (3)  
Pre-requisite(s): CHE 4322  

Principles of classical and statistical thermodynamics.

CHE 5322  Chemical Kinetics and Mechanisms  (3)  
Pre-requisite(s): CHE 4322  

Theory of rate processes and the use of kinetic data in the interpretation of reaction mechanisms.

CHE 5323  Structural Studies by X-ray Crystallography  (3)  
Pre-requisite(s): CHE 4324  

Preliminary studies of X-ray structure determination and solving the phase problem by various techniques to be learned before employing methods of structural refinement. Results and conclusions derived from refined structures will be applied to chemical research problems. Practical experience of crystal structure analysis will be the main emphasis.

CHE 5325  Quantum Chemistry  (3)  
Pre-requisite(s): CHE 4322  

Comparison of classical and quantum mechanics and application of quantum mechanics to electronic structure of the atoms and to the study of molecules and chemical bonds.

CHE 5326  Lasers and Molecular Spectroscopy  (3)  
Pre-requisite(s): CHE 4321 and 4322  

Properties of lasers and the fundamental principles of laser operation. Modern application of lasers to the study of spectroscopy and energy flow in atoms and molecules.

CHE 5331  Stereochemistry  (3)  
Pre-requisite(s): CHE 3332 and credit or concurrent enrollment in CHE 4322  

The stereochemistry of compounds of carbon and other elements, steric effects on physical and chemical properties of compounds, and recent developments in the field.

CHE 5334  Heterocyclic Chemistry  (3)  
Pre-requisite(s): CHE 3238, 3332 with grades of B or above; or consent of instructor  

The chemistry of heterocyclic compounds including substances containing nitrogen, oxygen, and sulfur. Synthesis, typical reactions and reaction mechanisms will be emphasized.

CHE 5335  Physical Organic Chemistry  (3)  
Pre-requisite(s): CHE 3238 and 3332 with grades of B or above; and credit or concurrent enrollment in CHE 4321; or consent of instructor  

Organic reaction mechanisms, including kinetics, steric and electronic effects, and molecular orbital considerations.

CHE 5336  Advanced Synthesis and Natural Products  (3)  
Pre-requisite(s): CHE 4332 or consent of instructor  

A study of modern synthetic organic chemistry with particular emphasis on the synthesis of complex natural products and reaction mechanisms.

CHE 5345  Selected Topics in Bioanalytical Chemistry  (3)  

This current topics course covers current breakthroughs in the development and application of bioanalytical tools. Applications of bioanalytical tools in fundamental biochemical science, as well as in biomedical applications, are included.

CHE 5346  Chemical Biology  (3)  
Pre-requisite(s): CHE 4341 or BIO 4307  

Revolutionary transformations in chemistry and biology have led to a merging at the boundary of these disciplines where contributions from both fields impact our molecular and quantitative understanding of biology. This course covers current research in chemical biology with a focus on enzyme mechanisms, molecular probes, biological pathways, chemical tools, and analytical methods to study biology, while also harnessing biological activity for chemical syntheses and commercial applications.

CHE 5347  Physical Biochemistry  (3)  
Pre-requisite(s): CHE 4341 or BIO 4341; and CHE 4321 or 4327; or consent of instructor  

Theory and applications of physical chemistry to systems of biological interest including such topics as reaction kinetics, protein folding and denaturation, ligand interactions, x-ray diffraction of proteins and nuclear magnetic resonance spectroscopy.

CHE 5348  Enzymology  (3)  
Pre-requisite(s): CHE 4341 or BIO 4307  

Kinetics, mechanisms, regulation, and other topics related to enzyme-catalyzed reactions.

CHE 5380  Principles of Biochemistry  (3)  
Pre-requisite(s): At least one year of course work in each of the following: chemistry, physics, organic chemistry, biology  

In addition to concurrent enrollment in the Medical Sciences M.S. degree program. Online biochemistry course for students in the Medical Sciences Master's degree program. Foundational principles of molecular structure and function are followed by in-depth study of biomolecules, enzymatic processes, and metabolic pathways.

CHE 5V60  Advanced Special Topics in Chemistry  (1-3)  

Topics in chemistry that are not covered in other graduate chemistry courses. May be repeated for credit if topic is different.

CHE 5V98  Graduate Research  (1-10)  
Pre-requisite(s): Graduate standing  

Required of all graduate students. For research credit prior to admission to candidacy for an advanced degree. Credit will be given for the amount of work done. May be repeated for credit through 45 hours.

CHE 5V99  Thesis  (1-9)  

Credit for the amount of work done. In no case will fewer than six semester hours be accepted for a thesis. Required of all master's students.

CHE 6V99  Dissertation  (1-9)  

Required of all doctoral candidates. In no case will fewer than twelve semester hours be accepted for a dissertation.